Posted By: CustomVite Nutrition Team Date: August 1, 2018 Comments: 0

Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders affecting approximately 6-20% of reproductive-age women.  PCOS happens when a woman’s body produces more male hormones (androgens) than normal, and thus causes an imbalance between their levels of estrogen and androgen hormones. Some symptoms include:

  • Menstrual disorders (often skipped cycles)
  • Hirsutism (male-pattern hair growth on the face, chest, or back)
  • Obesity
  • Impaired glucose tolerance
  • Hyperlipidemia
  • Elevated levels of inflammatory markers
  • Infertility
  • Sleep apnea
  • Anxiety and/or depression

Unfortunately, women with PCOS are at increased risk for diabetes, cardiovascular disease, endometrial cancer, and pregnancy complications such as gestational diabetes and preeclampsia.

NUTRITION:  Nutrition can play an important role in managing hormones, symptoms, and minimizing disease risk later in life. Although medications such as oral contraceptives are commonly used, lifestyle changes are a key part of managing PCOS. A low calorie, low carbohydrate diet, high in fiber, and low in sodium have been shown to help patients with PCOS improve hormonal balance, regulate menstrual cycles, restore ovulation, normalize sex hormones, achieve weight loss and reduce insulin resistance.

SUPPLEMENTS:  In addition to diet and exercise, several nutritional supplements may have beneficial effects and should be considered for the management of PCOS. Some of these supplements include:

  • Omega-3 Fish Oil
  • Borage Oil
  • Inositol
  • Berberine
  • Alpha Lipoic Acid
  • Magnesium
  • Vitamin D
  • NAC

 

 

References:

(1) An, Y., Sun, Z., Zhang, Y., Liu, B., Guan, Y., & Lu, M. (2013). The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment. Clinical Endocrinology, 80(3), 425-431. doi:10.1111/cen.12294

(2) Azadi-Yazdi, M., Nadjarzadeh, A., Khosravi-Boroujeni, H., & Salehi-Abargouei, A. (2017). The Effect of Vitamin D Supplementation on the Androgenic Profile in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Clinical Trials. Hormone and Metabolic Research, 49(03), 174-179. doi:10.1055/s-0043-103573

(3) Dietary Recommendations and Supplements for Women With PCOS. (n.d.). Retrieved from https://www.consultant360.com/n411/articles/dietary-recommendations-and-supplements-women-pcos/page/0/2

(4) Fulghesu, A. (2002). N-acetyl-cysteine treatment improves insulin sensitivity in women with polycystic ovary syndrome. Fertility and Sterility, 77(6), 1128-1135. doi:10.1016/s0015-0282(02)03133-3

(5) Javanmanesh, F., Kashanian, M., Rahimi, M., & Sheikhansari, N. (2015). A comparison between the effects of metformin andN-acetyl cysteine (NAC) on some metabolic and endocrine characteristics of women with polycystic ovary syndrome. Gynecological Endocrinology, 32(4), 285-289. doi:10.3109/09513590.2015.1115974

(6) Li, L., Li, C., Pan, P., Chen, X., Wu, X., Ng, E. H., & Yang, D. (2015). A Single Arm Pilot Study of Effects of Berberine on the Menstrual Pattern, Ovulation Rate, Hormonal and Metabolic Profiles in Anovulatory Chinese Women with Polycystic Ovary Syndrome. Plos One, 10(12). doi:10.1371/journal.pone.0144072

(7) Mcgrice, M., & Porter, J. (2017). The Effect of Low Carbohydrate Diets on Fertility Hormones and Outcomes in Overweight and Obese Women: A Systematic Review. Nutrients, 9(3), 204. doi:10.3390/nu9030204

(8) Moll, E. (2012). Ovulation induction in women with newly diagnosed polycystic ovary syndrome: A randomised double blind clinical trial comparing clomiphene citrate plus metformin with clomiphene citrate plus placebo. Http://isrctn.org/. doi:10.1186/isrctn55906981

(9) Nestler, J. E., & Laganà, A. S. (2018). Inositols. Infertility in Women with Polycystic Ovary Syndrome, 213-226. doi:10.1007/978-3-319-45534-1_16

(10) Oner, G., & Muderris, I. I. (2011). Clinical, endocrine and metabolic effects of metformin vs N-acetyl-cysteine in women with polycystic ovary syndrome. European Journal of Obstetrics & Gynecology and Reproductive Biology,159(1), 127-131. doi:10.1016/j.ejogrb.2011.07.005

(11) Pal, L., Berry, A., Coraluzzi, L., Kustan, E., Danton, C., Shaw, J., & Taylor, H. (2012). Therapeutic implications of vitamin D and calcium in overweight women with polycystic ovary syndrome. Gynecological Endocrinology,28(12), 965-968. doi:10.3109/09513590.2012.696753

(12) Polycystic ovary syndrome (PCOS). (2017, August 29). Retrieved from https://www.mayoclinic.org/diseases-conditions/pcos/symptoms-causes/syc-20353439

(13) Sadeghi, A., Djafarian, K., Mohammadi, H., & Shab-Bidar, S. (2017). Effect of omega-3 fatty acids supplementation on insulin resistance in women with polycystic ovary syndrome: Meta-analysis of randomized controlled trials. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 11(2), 157-162. doi:10.1016/j.dsx.2016.06.025

(14) Thakker, D., Raval, A., Patel, I., & Walia, R. (2013). N-acetylcysteine for polycystic ovary syndrome: A systematic review and meta-analysis of randomised controlled clinical trials. Value in Health, 16(3). doi:10.1016/j.jval.2013.03.779

(15) Thomson, R. L., Spedding, S., & Buckley, J. D. (2012). Vitamin D in the aetiology and management of polycystic ovary syndrome. Clinical Endocrinology, 77(3), 343-350. doi:10.1111/j.1365-2265.2012.04434.x


Leave a Reply

Your email address will not be published.

*
*

Copyright @ 2014 NutriLab LLC. All rights reserved
Designed By: Avion Technology Inc.